Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530703 | 0.90 | EDNRA (0.38) | EDNRA | |
| SCHEMBL4774085 | 0.90 | EDNRA (0.36) | EDNRA | |
| SCHEMBL4772914 | 0.89 | EDNRA (0.38) | EDNRA | |
| SCHEMBL4770207 | 0.89 | EDNRA (0.33) | EDNRA | |
| SCHEMBL4773473 | 0.88 | EDNRA (0.33) | EDNRA | |
| SCHEMBL5530883 | 0.87 | EDNRA (0.42) | EDNRA | |
| SCHEMBL4775956 | 0.87 | EDNRA (0.38) | EDNRA | |
| SCHEMBL4774269 | 0.87 | EDNRA (0.34) | EDNRA | |
| SCHEMBL4770957 | 0.86 | EDNRA (0.34) | EDNRA | |
| SCHEMBL5791432 | 0.86 | EDNRA (0.36) | EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237888-B1 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2006-09-13 | — | — | EP | disclosed |