Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531220 | 0.91 | EDNRA (0.37) | EDNRA | |
| SCHEMBL5787828 | 0.90 | EDNRA (0.37) | EDNRA | |
| SCHEMBL4772907 | 0.89 | EDNRA (0.35) | EDNRA | |
| SCHEMBL4771374 | 0.88 | EDNRA (0.32) | EDNRA | |
| SCHEMBL5531005 | 0.88 | EDNRA (0.41) | EDNRA | |
| SCHEMBL4770730 | 0.88 | EDNRA (0.38) | EDNRA | |
| SCHEMBL4767237 | 0.88 | EDNRB (0.39) | EDNRA | |
| SCHEMBL4774149 | 0.87 | EDNRA (0.34) | EDNRA | |
| SCHEMBL4765078 | 0.87 | EDNRA (0.38) | EDNRA | |
| SCHEMBL4770728 | 0.86 | EDNRA (0.38) | EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2002837-A1 | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-17 | — | — | EP | disclosed |