Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30150593 | 0.96 | RAB9A (0.62) | RAB9AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL1323646 | 0.96 | RAB9A (0.62) | RAB9AMAPTNPSR1MAPK1MEN1 | |
| Bromide SCHEMBL27462942 | 0.95 | RAB9A (0.60) | RAB9AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL6238551 | 0.88 | RAB9A (0.55) | RAB9AMAPTNPSR1MAPK1MEN1 | |
| Acetic Acid SCHEMBL27351298 | 0.87 | KMT2A (0.58) | RAB9AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL7539917 | 0.86 | RAB9A (0.60) | RAB9AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL7311175 | 0.85 | MAPK1 (0.65) | RAB9AMAPK1MEN1KMT2AGRM2 | |
| SCHEMBL4313839 | 0.85 | MAPK1 (0.61) | RAB9AMAPTNPSR1MAPK1MEN1 | |
| Ethoxycarbonyl Group SCHEMBL27686480 | 0.81 | RAB9A (0.51) | RAB9AMAPTNPSR1MAPK1MEN1 | |
| SCHEMBL24932986 | 0.81 | RAB9A (0.61) | RAB9AMAPTNPSR1MAPK1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664018-A1 | BIPYRIDYL AMINES AND ETHERS AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 | Merck & Co., Inc. (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005021529-A1 | BIPYRIDYL AMINES AND ETHERS AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 | MERCK & CO., INC. (US) | 2005-03-10 | — | — | WO | disclosed |