Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.56 |
| ▸ | SELP | P16109 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5788972 | 0.86 | PRKCI (0.51) | SELLSELPALDH1A1HPGDKDM4E | |
| SCHEMBL9328643 | 0.84 | SELL (0.58) | SELLSELPALDH1A1HPGDKDM4E | |
| SCHEMBL6683046 | 0.83 | SELL (0.47) | SELLSELPGABRA1GABRB2ALDH1A1 | |
| SCHEMBL7728985 | 0.82 | GABRA1 (0.43) | SELLSELPGABRA1GABRB2ALDH1A1 | |
| SCHEMBL28750906 | 0.82 | CLCN2 (0.48) | SELLSELPGABRA1GABRB2ALDH1A1 | |
| SCHEMBL7521299 | 0.81 | PPARA (0.54) | — | |
| SCHEMBL29695710 | 0.81 | HMGB1 (0.65) | SELLSELPGABRA1GABRB2ALDH1A1 | |
| SCHEMBL39623 | 0.81 | HMGB1 (0.65) | SELLSELPGABRA1GABRB2ALDH1A1 | |
| SCHEMBL29860525 | 0.81 | SELL (0.79) | SELLSELPALDH1A1HPGDKDM4E | |
| SCHEMBL45861 | 0.81 | GABRA1 (0.68) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041448-B1 | Method for decoloring | TOSHIBA KK (JP) | 2006-06-07 | — | — | EP | claimed |
| CN-115281218-A | Application of trichoderma fermentation liquor extract | 贵州省生物技术研究所(贵州省生物技术重点实验室、贵州省马铃薯研究所、贵州省食品加工研究所) | 2022-11-04 | — | — | CN | disclosed |
| EP-3645707-A1 | METHOD FOR PRODUCING ERYTHROID PROGENITOR CELLS | Etablissement Français du Sang (FR) | 2020-05-06 | — | — | EP | disclosed |
| US-9079989-B2 | Charge control resin and manufacturing method of the same | ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) | 2015-07-14 | — | — | US | disclosed |
| US-20150025213-A1 | CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME | ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) | 2015-01-22 | — | — | US | disclosed |
| US-8883946-B2 | Charge control resin and manufacturing method of the same | ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20140080989-A1 | CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME | ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| WO-2013187971-A2 | MACROCYCLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-12-19 | — | — | WO | disclosed |
| CN-102321033-B | Preparation method of tarceva | JIANGSU HUIFENG AGROCHEMICAL CO LTD | 2013-10-09 | — | — | CN | disclosed |
| CN-102321033-A | Preparation method of tarceva | JIANGSU HUIFENG AGROCHEMICAL CO LTD | 2012-01-18 | — | — | CN | disclosed |
| US-20030050306-A1 | Novel heteroaryl derivatives, their preparation and use | H. LUNDBECK A/S (DK) | 2003-03-13 | — | — | US | disclosed |
| EP-1246820-A1 | NOVEL HETEROARYL DERIVATIVES, THEIR PREPARATION AND USE | H. LUNDBECK A/S (DK) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049683-A1 | NOVEL HETEROARYL DERIVATIVES, THEIR PREPARATION AND USE | H. LUNDBECK A/S (DK) | 2001-07-12 | — | — | WO | disclosed |
| EP-0604494-B1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-28 | — | — | EP | disclosed |
| US-5580885-A | FOR TREATMENT OF GASTROINTESTINAL, CARDIOVASCULAR OR NERVOUS SYSTEM DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-12-03 | — | — | US | disclosed |
| EP-0604494-A1 | 5-HT 4? RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-06 | — | — | EP | disclosed |
| WO-1993005038-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050306-A1 | Novel heteroaryl derivatives, their preparation and use | CRBN, CDR2, DRD3 | SELL 3070/4885SELP 2754/4885GABRA1 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.