Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.72 |
| ▸ | PLD2 | O14939 | 1/20 | 0.48 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5788303 | 0.92 | CTSS (0.73) | CTSSPLD2PLD1OPRM1OPRL1 | |
| SCHEMBL5532982 | 0.90 | CTSS (0.76) | CTSSPLD2PLD1 | |
| SCHEMBL5787032 | 0.85 | CTSS (0.77) | CTSS | |
| SCHEMBL4713263 | 0.85 | CTSS (0.76) | CTSSPLD2PLD1 | |
| SCHEMBL4713169 | 0.84 | CTSS (1.00) | CTSS | |
| SCHEMBL5788301 | 0.81 | CTSS (0.72) | CTSS | |
| SCHEMBL5788731 | 0.81 | CTSS (0.73) | CTSS | |
| SCHEMBL14536220 | 0.81 | CTSS (0.87) | CTSS | |
| SCHEMBL5789183 | 0.80 | CTSS (0.76) | CTSS | |
| SCHEMBL5533946 | 0.77 | CTSS (0.90) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309593-B1 | SUBSTITUTED PYRAZOLES | ORTHO MCNEIL PHARM INC (US) | 2006-03-15 | — | — | EP | claimed |