Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 19/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5789734 | 0.89 | KIF11 (0.42) | KIF11 | |
| SCHEMBL4039076 | 0.86 | KIF11 (0.60) | KIF11 | |
| SCHEMBL5789424 | 0.82 | KIF11 (0.52) | KIF11 | |
| SCHEMBL5787729 | 0.82 | KIF11 (0.61) | KIF11 | |
| SCHEMBL5791893 | 0.81 | KIF11 (0.54) | KIF11 | |
| SCHEMBL5787536 | 0.80 | KIF11 (0.66) | KIF11 | |
| SCHEMBL5783480 | 0.80 | KIF11 (0.52) | KIF11 | |
| SCHEMBL5789930 | 0.79 | KIF11 (0.44) | KIF11 | |
| SCHEMBL5810502 | 0.78 | KIF11 (0.42) | KIF11 | |
| SCHEMBL5789333 | 0.77 | KIF11 (0.43) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628981-A2 | BICYCLICPYRIMIDONES AND THEIR USE TO TREAT DISEASES | Bristol-Myers Squibb Company (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004106492-A2 | BICYCLICPYRIMIDONES AND THEIR USE TO TREAT DISEASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-09 | — | — | WO | disclosed |