SCHEMBL5789016

SCHEMBL5789016

OCC(c1ccccc1)C1CN1CCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.48
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
GBA1 P04062 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7696271 0.81 HTR2A (0.56) GAAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL7695220 0.81 GAA (0.39) GAAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL7692426 0.78 SIGMAR1 (0.45) GAAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL7694378 0.76 GAA (0.48) GAAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL7693891 0.76 GAA (0.48) GAAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL7694900 0.76 GAA (0.48) GAAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL7688299 0.75 GAA (0.47) GAAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL5789012 0.75 GAA (0.47) GAAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL7695135 0.75 GAA (0.47) GAAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL7691972 0.74 GAA (0.46) GAAKDM4ECYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006004359-A1 SPHINGOLIPID DERIVATIVES AND THE COMPOSITION FOR ANTI-CANCER CONTAINING THE SAME DOOSAN CORPORATION (KR) 2006-01-12 WO disclosed
WO-2002012184-A1 PROCESS FOR PREPARING ALPHA-AMINO ACIDS AND THEIR DERIVATIVES INCLUDING PHENYLALANINE AND HOMOPHENYLALANINE AND THEIR INTERMEDIATES CHEMBIONEX CO., LTD. (KR) 2002-02-14 WO disclosed