Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 12/20 | 0.57 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784277 | 0.93 | AVPR2 (0.51) | AVPR2AVPR1AROCK2PDE4APDE4B | |
| SCHEMBL5785257 | 0.93 | AVPR2 (0.52) | AVPR2AVPR1AROCK2PDE4APDE4B | |
| SCHEMBL5785906 | 0.91 | AVPR2 (0.49) | AVPR2AVPR1AROCK2PDE4APDE4B | |
| SCHEMBL5783851 | 0.91 | AVPR1A (0.54) | AVPR2AVPR1A | |
| SCHEMBL5785002 | 0.89 | AVPR2 (0.48) | AVPR2AVPR1AROCK2PDE4APDE4B | |
| SCHEMBL5784716 | 0.89 | AVPR2 (0.52) | AVPR2AVPR1AROCK2PDE4APDE4B | |
| SCHEMBL5787177 | 0.88 | AVPR2 (0.47) | AVPR2AVPR1AROCK2PDE4APDE4B | |
| SCHEMBL5786566 | 0.88 | AVPR2 (0.54) | AVPR2AVPR1AROCK2PDE4APDE4B | |
| SCHEMBL5784158 | 0.88 | AVPR2 (0.49) | AVPR2AVPR1AROCK2PDE4APDE4B | |
| SCHEMBL6632264 | 0.87 | AVPR2 (0.52) | AVPR2AVPR1AROCK2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377586-B1 | TRICYCLIC DIAZEPINES AS TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | WYETH CORP (US) | 2006-03-22 | — | — | EP | claimed |