Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5719238 | 0.92 | DPP4 (0.52) | DPP4L3MBTL1ALDH1A1HTR2AKMT2A | |
| SCHEMBL5789482 | 0.86 | DPP4 (0.50) | DPP4L3MBTL1ALDH1A1NPSR1LMNA | |
| SCHEMBL5718847 | 0.85 | DPP4 (0.58) | DPP4ALDH1A1KMT2ANPSR1HTT | |
| SCHEMBL5719678 | 0.84 | DPP4 (0.68) | DPP4L3MBTL1ALDH1A1HTR2AKMT2A | |
| SCHEMBL5775361 | 0.83 | DPP4 (0.45) | DPP4L3MBTL1ALDH1A1HTR2AKMT2A | |
| Trifluoroacetic Acid SCHEMBL5719045 | 0.83 | DPP4 (0.53) | DPP4L3MBTL1ALDH1A1HTR2AKMT2A | |
| SCHEMBL5788736 | 0.83 | LMNA (0.48) | DPP4L3MBTL1ALDH1A1HTR2ANPSR1 | |
| SCHEMBL5789590 | 0.82 | DPP4 (0.59) | DPP4L3MBTL1ALDH1A1HTR2ALMNA | |
| Trifluoroacetic Acid SCHEMBL5773381 | 0.82 | DPP4 (0.46) | DPP4L3MBTL1ALDH1A1NPSR1LMNA | |
| Trifluoroacetic Acid SCHEMBL5719321 | 0.82 | DPP4 (0.52) | DPP4L3MBTL1ALDH1A1HTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | claimed |
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | claimed |
| US-7074798-B2 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD (JP) | 2006-07-11 | — | — | US | disclosed |
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | DPP4, DPP9, DPP7 | DPP4 1/4885L3MBTL1 1200/4885ALDH1A1 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.