Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913995 | 0.91 | KDM4E (0.47) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL916437 | 0.90 | KDM4E (0.46) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL915375 | 0.84 | L3MBTL1 (0.43) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL397240 | 0.81 | HRH4 (0.56) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL916394 | 0.78 | KDM4E (0.39) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL914953 | 0.76 | KDM4E (0.50) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL913978 | 0.76 | KDM4E (0.55) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL699482 | 0.75 | FLT3 (0.60) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL914562 | 0.75 | KDM4E (0.52) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL914726 | 0.74 | KDM4E (0.50) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-A2 | CHEMOKINE RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005077932-A2 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2005-08-25 | — | — | WO | disclosed |