SCHEMBL5789684

SCHEMBL5789684

Cc1noc(=O)c2ccc(NC(=O)C(=O)CC3(C4CCCC4)CCCc4ccccc43)cc12

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31734235 0.83 NR3C1 (1.00) NR3C1
SCHEMBL6584187 0.78 NR3C1 (0.52) NR3C1
SCHEMBL6585728 0.77 NR3C1 (0.51) NR3C1
SCHEMBL6585630 0.77 NR3C1 (0.51) NR3C1
SCHEMBL4622178 0.76 NR3C1 (0.49) NR3C1
SCHEMBL5645631 0.76 NR3C1 (0.48) NR3C1
SCHEMBL4740189 0.74 NR3C1 (0.57) NR3C1
SCHEMBL4279436 0.72 NR3C1 (0.52) NR3C1
SCHEMBL4281052 0.71 NR3C1 (0.53) NR3C1
SCHEMBL5789675 0.70 NR3C1 (0.44) NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006000401-A1 SUBSTITUTED OXAZINES AS GLUCOCORTICOID RECEPTOR MODULATORS GLAXO GROUP LIMITED (GB) 2006-01-05 WO disclosed