Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 15/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5753476 | 0.92 | GNRHR (0.69) | GNRHR | |
| SCHEMBL14424656 | 0.91 | GNRHR (0.75) | GNRHR | |
| SCHEMBL8695273 | 0.90 | GNRHR (1.00) | GNRHR | |
| SCHEMBL5755164 | 0.90 | GNRHR (0.73) | GNRHR | |
| SCHEMBL5755162 | 0.90 | GNRHR (0.73) | GNRHR | |
| SCHEMBL5789794 | 0.87 | GNRHR (0.72) | GNRHR | |
| SCHEMBL14424655 | 0.86 | GNRHR (0.69) | GNRHR | |
| SCHEMBL8569672 | 0.81 | GNRHR (0.66) | GNRHR | |
| SCHEMBL5760695 | 0.80 | GNRHR (0.62) | GNRHR | |
| SCHEMBL14424652 | 0.80 | GNRHR (0.61) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363903-B1 | INDOLE DERIVATIVES AND THEIR USE AS GNRH ANTAGONISTS | ASTRAZENECA AB (SE) | 2006-10-11 | — | — | EP | claimed |