Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 18/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784486 | 0.89 | KIF11 (0.58) | KIF11 | |
| SCHEMBL5790136 | 0.86 | KIF11 (0.62) | KIF11 | |
| SCHEMBL5787320 | 0.85 | KIF11 (0.51) | KIF11 | |
| SCHEMBL5785400 | 0.83 | KIF11 (0.49) | KIF11 | |
| SCHEMBL5789734 | 0.77 | KIF11 (0.42) | KIF11 | |
| SCHEMBL5783480 | 0.77 | KIF11 (0.52) | KIF11 | |
| SCHEMBL5784446 | 0.77 | KIF11 (0.68) | KIF11 | |
| SCHEMBL5899051 | 0.77 | KIF11 (0.63) | KIF11 | |
| SCHEMBL5787729 | 0.76 | KIF11 (0.61) | KIF11 | |
| SCHEMBL5801696 | 0.76 | KIF11 (0.48) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628981-A2 | BICYCLICPYRIMIDONES AND THEIR USE TO TREAT DISEASES | Bristol-Myers Squibb Company (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004106492-A2 | BICYCLICPYRIMIDONES AND THEIR USE TO TREAT DISEASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-09 | — | — | WO | disclosed |