Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1873995 | 0.87 | KMT2A (0.50) | KMT2AMEN1RAB9ACYP2C19CYP2D6 | |
| SCHEMBL29823211 | 0.87 | KMT2A (0.50) | KMT2AMEN1RAB9ACYP2C19CYP2D6 | |
| SCHEMBL1872883 | 0.85 | MEN1 (0.41) | KMT2AMEN1RAB9ACYP2C19CYP2D6 | |
| SCHEMBL29823986 | 0.85 | MEN1 (0.41) | KMT2AMEN1RAB9ACYP2C19CYP2D6 | |
| SCHEMBL29823495 | 0.81 | CCR3 (0.45) | KMT2AMEN1ALDH1A1CCR3KDM4E | |
| SCHEMBL1870607 | 0.81 | CCR3 (0.45) | KMT2AMEN1ALDH1A1CCR3KDM4E | |
| SCHEMBL29823344 | 0.81 | CXCR4 (0.51) | KMT2AMEN1RAB9AALDH1A1KDM4E | |
| SCHEMBL1879660 | 0.81 | CXCR4 (0.51) | KMT2AMEN1RAB9AALDH1A1KDM4E | |
| SCHEMBL29823437 | 0.80 | CCR1 (0.42) | KMT2AMEN1ALDH1A1CCR3LMNA | |
| SCHEMBL1879075 | 0.80 | CCR1 (0.42) | KMT2AMEN1ALDH1A1CCR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163238-B1 | CHEMOKINE RECPETOR BINDING HETEROCYCLIC COMPOUNDS | ANORMED INC (CA) | 2006-05-31 | — | — | EP | disclosed |