SCHEMBL29823211

SCHEMBL29823211

CCCCN1CCC(N(CCc2ccccn2)Cc2cccc(CNCc3ccccn3)c2)CC1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.50
▸ MEN1 O00255 2/20 0.49
▸ RAB9A P51151 1/20 0.49
▸ DCUN1D1 Q96GG9 10/20 0.40
▸ UBE2M P61081 9/20 0.40
▸ CYP2D6 P10635 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ ALDH1A1 P00352 3/20 0.38
▸ OPRM1 P35372 1/20 0.38
▸ OPRD1 P41143 1/20 0.38
▸ OPRK1 P41145 1/20 0.38
▸ CCR3 P51677 1/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1873995 1.00 KMT2A (0.50) KMT2AMEN1RAB9ADCUN1D1UBE2M
SCHEMBL5790256 0.87 KMT2A (0.41) KMT2AMEN1RAB9ACYP2D6CYP2C9
SCHEMBL1872883 0.84 MEN1 (0.41) KMT2AMEN1RAB9ACYP2D6CYP2C9
SCHEMBL29823986 0.84 MEN1 (0.41) KMT2AMEN1RAB9ACYP2D6CYP2C9
SCHEMBL29823495 0.80 CCR3 (0.45) KMT2AMEN1ALDH1A1CCR3TSHR
SCHEMBL1870607 0.80 CCR3 (0.45) KMT2AMEN1ALDH1A1CCR3TSHR
SCHEMBL29823344 0.80 CXCR4 (0.51) KMT2AMEN1RAB9AALDH1A1
SCHEMBL1879660 0.80 CXCR4 (0.51) KMT2AMEN1RAB9AALDH1A1
SCHEMBL5603877 0.79 CARM1 (0.42) KMT2ADCUN1D1UBE2MCYP2D6CYP2C9
SCHEMBL28438648 0.76 CCR1 (0.42) KMT2AMEN1ALDH1A1CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025230907-A1 A CXCR4 ANTAGONIST, A STATS ACTIVATOR, AND/OR AN AGENT THAT INCREASES NITRIC OXIDE CONTENT FOR USE IN METHODS OF IMPROVING NERVE REGENERATION THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-11-06 — — WO disclosed
EP-4308694-A1 DOSING REGIMENS FOR HEMATOPOIETIC STEM CELL MOBILIZATION FOR STEM CELL TRANSPLANTS IN MULTIPLE MYELOMA PATIENTS Magenta Therapeutics, Inc. (US) 2024-01-24 — — EP disclosed
CN-115997009-A Methods and compositions for in vivo transduction of hematopoietic stem and progenitor cells 美真达治疗公司 2023-04-21 — — CN disclosed
EP-4143302-A1 METHODS AND COMPOSITIONS FOR TRANSDUCING HEMATOPOIETIC STEM AND PROGENITOR CELLS IN VIVO Magenta Therapeutics, Inc. (US) 2023-03-08 — — EP disclosed
WO-2022197776-A1 DOSING REGIMENS FOR HEMATOPOIETIC STEM CELL MOBILIZATION FOR STEM CELL TRANSPLANTS IN MULTIPLE MYELOMA PATIENTS Magenta Therapeutics, Inc. (US) 2022-09-22 — — WO disclosed
EP-4051298-A1 DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENTOR CELLS Magenta Therapeutics, Inc. (US) 2022-09-07 — — EP disclosed
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