Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | FABP3 | P05413 | 7/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL3936260 | 0.96 | CA1 (0.55) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Azelaic Acid SCHEMBL29913797 | 0.96 | CA1 (0.55) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL4369554 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL5146021 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL3684383 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL11050745 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL8006228 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL1194225 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL3137967 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL9820842 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642679-B2 | Dental cement composition | GC CORPORATION (JP) | 2014-02-04 | — | — | US | claimed |
| EP-2416756-A2 | STABLE PHARMACEUTICAL COMPOSITIONS WITH HIGH BIOAVAILIBILITY | Bilgic, Mahmut (TR) | 2012-02-15 | — | — | EP | claimed |
| EP-2266584-A2 | Composition with strontium and vitamin D for the prophylaxis and/or treatment of cartilage and/or bone conditions | Osteologix A/S (DK) | 2010-12-29 | — | — | EP | claimed |
| WO-2010117346-A2 | STABLE PHARMACEUTICAL COMPOSITIONS WITH HIGH BIOAVAILIBILITY | BILGIC MAHMUT (TR) | 2010-10-14 | — | — | WO | claimed |
| US-20100068678-A1 | CEMENT FOR SEALER | GC CORPORATION (JP) | 2010-03-18 | — | — | US | claimed |
| EP-2163232-A1 | Cement for sealer | GC Corporation (JP) | 2010-03-17 | — | — | EP | claimed |
| EP-0416321-B1 | Crystalline polyolefin composition | CHISSO CORP (JP) | 1994-11-09 | — | — | EP | claimed |
| US-5063264-A | Molding materials | CHISSO CORPORATION (JP) | 1991-11-05 | — | — | US | claimed |
| EP-0416321-A1 | Crystalline polyolefin composition | Chisso Corporation (JP) | 1991-03-13 | — | — | EP | claimed |
| EP-3830315-B1 | HEAT TRANSFER FLUIDS CONTAINING SYNERGISTIC BLENDS OF CORROSION INHIBITOR FORMULATIONS | PRESTONE PRODUCTS CORP (US) | 2025-07-16 | — | — | EP | disclosed |
| EP-3484976-B1 | HEAT TRANSFER FLUIDS AND METHODS FOR PREVENTING CORROSION IN HEAT TRANSFER SYSTEMS | PRESTONE PRODUCTS CORP (US) | 2024-05-29 | — | — | EP | disclosed |
| CN-112996951-B | Heat transfer fluids containing synergistic blends of corrosion inhibitor formulations | 布拉斯通产品公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-107250318-B | Super concentrate additive solution compositions | 布拉斯通产品公司 | 2023-10-27 | — | — | CN | disclosed |
| US-11639457-B2 | Heat transfer fluids and methods for preventing corrosion in heat transfer systems | PRESTONE PRODUCTS CORPORATION (US) | 2023-05-02 | — | — | US | disclosed |
| EP-2163232-A1 | Cement for sealer | GC Corporation (JP) | 2010-03-17 | — | — | EP | disclosed |
| US-5645634-A | Composition and method for forming Ba1-X Srx Tiy O3 thin films | MITSUBISHI MATERIALS CORPORATION (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0416321-B1 | Crystalline polyolefin composition | CHISSO CORP (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-5063264-A | Molding materials | CHISSO CORPORATION (JP) | 1991-11-05 | — | — | US | disclosed |
| EP-0416321-A1 | Crystalline polyolefin composition | Chisso Corporation (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4130484-A | Purification process | PHILLIPS PETROLEUM COMPANY (US) | 1978-12-19 | — | — | US | disclosed |