Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025081 | 0.92 | DDB1 (0.48) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL16661304 | 0.90 | DDB1 (0.56) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL13993260 | 0.87 | SMN1; SMN2 (0.47) | DDB1CRBNKMT2ACYP2C19SMN1; SMN2 | |
| SCHEMBL1200111 | 0.86 | DDB1 (0.54) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL3615694 | 0.83 | ALDH1A1 (0.58) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL18493339 | 0.83 | DDB1 (0.54) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL25317301 | 0.82 | ALDH1A1 (0.51) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7228727 | 0.81 | DDB1 (0.52) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL15105826 | 0.81 | ALDH1A1 (0.54) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| Fluoride SCHEMBL27773141 | 0.81 | ALDH1A1 (0.50) | DDB1CRBNALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016237-A2 | HETEROCYCLIC DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-16 | — | — | WO | claimed |
| WO-2005016884-A9 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2006-03-16 | — | — | WO | disclosed |