Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791529 | 1.00 | KDM1A (0.47) | KDM1AMAPTGAA | |
| SCHEMBL5793421 | 1.00 | KDM1A (0.47) | KDM1AMAPTGAA | |
| SCHEMBL5790516 | 0.80 | TAAR1 (0.36) | MAPTGAA | |
| SCHEMBL5793422 | 0.80 | TAAR1 (0.36) | MAPTGAA | |
| SCHEMBL5791532 | 0.80 | TAAR1 (0.36) | MAPTGAA | |
| SCHEMBL5791325 | 0.79 | KDM1A (0.49) | KDM1A | |
| SCHEMBL5794880 | 0.79 | KDM1A (0.49) | KDM1A | |
| SCHEMBL5794455 | 0.78 | KDM1A (0.48) | KDM1A | |
| SCHEMBL5821182 | 0.74 | KDM1A (0.46) | KDM1AMAPTGAA | |
| SCHEMBL5792160 | 0.74 | KDM1A (0.46) | KDM1AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | claimed |
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |