Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.76 |
| ▸ | CD74 | P04233 | 12/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790260 | 0.92 | CTSS (0.73) | CTSSCD74 | |
| SCHEMBL5532253 | 0.91 | CTSS (0.78) | CTSSCD74 | |
| SCHEMBL5538469 | 0.89 | CTSS (0.82) | CTSSCD74 | |
| SCHEMBL5533929 | 0.87 | CTSS (0.83) | CTSSCD74 | |
| SCHEMBL5535451 | 0.86 | CTSS (1.00) | CTSSCD74 | |
| SCHEMBL5788292 | 0.85 | CTSS (0.71) | CTSSCD74 | |
| SCHEMBL5532224 | 0.84 | CTSS (0.80) | CTSSCD74 | |
| SCHEMBL5532532 | 0.82 | CTSS (0.77) | CTSSCD74 | |
| SCHEMBL5528483 | 0.80 | CTSS (0.78) | CTSSCD74 | |
| SCHEMBL5534928 | 0.80 | CTSS (0.73) | CTSSCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309593-B1 | SUBSTITUTED PYRAZOLES | ORTHO MCNEIL PHARM INC (US) | 2006-03-15 | — | — | EP | claimed |