Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 4/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866815 | 0.84 | CYP1A1 (0.52) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL8649420 | 0.83 | AKR1C3 (0.56) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL8649414 | 0.83 | AKR1C3 (0.56) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL1762739 | 0.80 | MAPT (0.80) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL1762741 | 0.80 | MAPT (0.80) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL4098172 | 0.75 | CYP19A1 (0.43) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL8435518 | 0.74 | CYP1A1 (0.54) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL8647943 | 0.73 | CYP1A2 (0.47) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL15646031 | 0.71 | PKM (0.64) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL11818982 | 0.71 | PKM (0.64) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006006184-A2 | A PROCESS FOR THE MANUFACTURING OF LORATADINE AND ITS INTERMEDIATES | MOREPEN LABORATORIES LIMITED (IN) | 2006-01-19 | — | — | WO | disclosed |