Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790945 | 1.00 | MEN1 (0.41) | MEN1GAAMAPTKMT2AKDM4E | |
| SCHEMBL9064740 | 0.76 | AR (0.50) | ARHTR2AHTR2CHTR2B | |
| SCHEMBL30738393 | 0.75 | AR (0.52) | ARHTR2AHTR2CHTR2BKIF11 | |
| SCHEMBL27654170 | 0.75 | AR (0.52) | ARHTR2AHTR2CHTR2BKIF11 | |
| SCHEMBL1735450 | 0.74 | AR (0.43) | KMT2AARHTR2AHTR2CHTR2B | |
| SCHEMBL17026953 | 0.74 | AR (0.48) | GAAARBRD4CREBBPKIF11 | |
| SCHEMBL1735446 | 0.74 | AR (0.43) | KMT2AARHTR2AHTR2CHTR2B | |
| SCHEMBL12057414 | 0.74 | AR (0.52) | MEN1GAAMAPTKMT2AKDM4E | |
| SCHEMBL12156896 | 0.74 | AR (0.38) | KMT2AARCA1CA2BRD4 | |
| SCHEMBL31193465 | 0.74 | AR (0.43) | KMT2AARHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006009819-A1 | INHIBITORS OF CHOLESTERYL ESTER TRANSFER PROTIEN | ARRAY BIOPHARMA INC. (US) | 2006-01-26 | — | — | WO | disclosed |
| US-20050282812-A1 | Inhibitors of cholesteryl ester transfer protein | ARRAY BIOPHARMA INC. | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282812-A1 | Inhibitors of cholesteryl ester transfer protein | CETP, LCAT, MTTP | MEN1 4456/4885GAA 317/4885MAPT 2183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.