Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30738393 | 1.00 | AR (0.52) | ARSRD5A1PNMTHTR2AHTR2C | |
| SCHEMBL9064740 | 0.90 | AR (0.50) | ARPNMTHTR2AHTR2CHTR2B | |
| SCHEMBL6754129 | 0.90 | AR (0.46) | ARSRD5A1HTR2AHTR2CHTR2B | |
| SCHEMBL6754125 | 0.90 | AR (0.46) | ARSRD5A1HTR2AHTR2CHTR2B | |
| SCHEMBL6754126 | 0.90 | AR (0.46) | ARSRD5A1HTR2AHTR2CHTR2B | |
| Ethoxycarbonyl Group SCHEMBL29291835 | 0.88 | AR (0.46) | ARSRD5A1KIF11MTNR1A | |
| SCHEMBL22297852 | 0.87 | AR (0.44) | ARPNMTKIF11MTNR1A | |
| SCHEMBL6754201 | 0.85 | AR (0.38) | ARSRD5A1PNMTKIF11 | |
| SCHEMBL6754202 | 0.85 | AR (0.38) | ARSRD5A1PNMTKIF11 | |
| SCHEMBL6752929 | 0.85 | AR (0.40) | ARSRD5A1PNMTHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108558-B | The method that preparation is used to prepare the synthetic intermediate of tetrahydroquinoline derivative | 狄智玛制药私人有限公司 | 2019-11-19 | — | — | CN | disclosed |
| CN-100528878-C | Tetrahydroquinoline derivatives and process for producing the same | TANABE SEIYAKU CO (JP) | 2009-08-19 | — | — | CN | disclosed |
| CN-101381345-A | Tetrahydroquinoline derivatives and a process for preparing the same | TANABE SEIYAKU CO (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-1938314-A | Tetrahydroquinoline derivatives and process for producing the same | TANABE SEIYAKU CO (JP) | 2007-03-28 | — | — | CN | disclosed |