Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792778 | 0.90 | MAPK14 (0.57) | MAPK14CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL5789441 | 0.89 | MAPK14 (0.50) | MAPK14CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL3549439 | 0.85 | PDE4B (0.62) | MAPK14CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL5791454 | 0.85 | HTT (0.52) | MAPK14CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL5789709 | 0.84 | HTT (0.51) | MAPK14CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL5792828 | 0.83 | CYP2C9 (0.53) | MAPK14CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL5792547 | 0.82 | MAPK14 (0.55) | MAPK14CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL5807168 | 0.82 | MAPK14 (0.55) | MAPK14CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL5791336 | 0.81 | MAPK14 (0.49) | MAPK14CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL5790812 | 0.78 | GAA (0.57) | MAPK14CYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016237-A2 | HETEROCYCLIC DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-16 | — | — | WO | disclosed |