Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791336 | 0.93 | MAPK14 (0.49) | MAPK14CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL5790964 | 0.89 | MAPK14 (0.55) | MAPK14CYP2C9CYP2C19CYP46A1HTR2B | |
| SCHEMBL5790391 | 0.86 | HTT (0.46) | MAPK14CYP2C9CYP2C19HTR2BALDH1A1 | |
| SCHEMBL5791171 | 0.86 | MGLL (0.43) | MAPK14CYP2C9CYP2C19CYP46A1HTR2B | |
| SCHEMBL5792778 | 0.85 | MAPK14 (0.57) | MAPK14CYP2C9CYP2C19CYP46A1HTR2B | |
| SCHEMBL3549390 | 0.78 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL5792547 | 0.78 | MAPK14 (0.55) | MAPK14CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL3549439 | 0.78 | PDE4B (0.62) | MAPK14CYP2C9CYP2C19USP2ALDH1A1 | |
| SCHEMBL5807168 | 0.77 | MAPK14 (0.55) | MAPK14CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL5791473 | 0.77 | HTT (0.44) | MAPK14CYP2C9CYP2C19HTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016237-A2 | HETEROCYCLIC DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-16 | — | — | WO | disclosed |