SCHEMBL57910

SCHEMBL57910

Nc1ncccc1[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.56
POLB P06746 1/20 0.55
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
RAB9A P51151 2/20 0.53
ALDH1A1 P00352 4/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
NCOA1 Q15788 1/20 0.50
NCOA3 Q9Y6Q9 1/20 0.50
CYP2C19 P33261 1/20 0.50
MAPT P10636 5/20 0.49
GAA P10253 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 2/20 0.46
PAX8 Q06710 1/20 0.46
KDM4E B2RXH2 2/20 0.46
CTSB P07858 2/20 0.46
IDO1 P14902 1/20 0.46
TDO2 P48775 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9936980 1.00 PDE10A (0.56) PDE10APOLBMEN1KMT2ARAB9A
Hydrochloric Acid SCHEMBL2173960 0.98 PDE10A (0.55) PDE10APOLBMEN1KMT2ARAB9A
Ammonia Solution, Strong SCHEMBL28729548 0.98 PDE10A (0.55) PDE10APOLBMEN1KMT2ARAB9A
Bromide SCHEMBL27900894 0.98 PDE10A (0.55) PDE10APOLBMEN1KMT2ARAB9A
Nitrogen SCHEMBL28247482 0.96 PDE10A (0.53) PDE10APOLBMEN1KMT2ARAB9A
Acetic Acid SCHEMBL29111017 0.89 MEN1 (0.49) PDE10APOLBMEN1KMT2ARAB9A
SCHEMBL1648667 0.87 MAPT (0.49) PDE10APOLBMEN1KMT2ARAB9A
Piperidine SCHEMBL27606158 0.85 CYP1A2 (0.50) PDE10APOLBMEN1KMT2ARAB9A
SCHEMBL8402283 0.83 ALDH1A1 (0.50) PDE10APOLBMEN1KMT2ARAB9A
SCHEMBL7146668 0.80 NPC1 (0.51) POLBMEN1KMT2ARAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 924 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118406050-A Novel imidazo [1,2-a ] pyridine compound, and preparation method and application thereof 大连理工大学 2024-07-30 CN claimed
CN-114262293-B Preparation method of 2-amino-3-bromopyridine 上海有吉医药化工有限公司 2023-09-22 CN claimed
CN-109970633-B Pyridine sulfone and derivative, preparation method and application thereof 湖南化工研究院有限公司 2022-12-27 CN claimed
CN-113480541-B Process for producing imidazopyridine compound and intermediate thereof 湖南化工研究院有限公司 2022-09-02 CN claimed
CN-114262293-A Preparation method of 2-amino-3-bromopyridine 安徽有吉医药科技有限公司 2022-04-01 CN claimed
CN-107722240-B Resin composition, and prepreg, metal foil laminate and printed wiring board produced using the same 台燿科技股份有限公司 2020-10-23 CN claimed
US-10563006-B2 Resin composition, and prepreg, metal-clad laminate, and printed circuit board prepared using the same TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2020-02-18 US claimed
CN-107722240-A resin composition, and prepreg, metal foil laminate and printed wiring board produced using the same 台燿科技股份有限公司 2018-02-23 CN claimed
US-20180044467-A1 Resin Composition, and Prepreg, Metal-Clad Laminate, and Printed Circuit Board Prepared Using the Same TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2018-02-15 US claimed
CN-104163791-B N-pyridine (hetero) aryl amide compound and preparation method and application thereof 湖南化工研究院 2017-05-03 CN claimed
US-5498715-A Process for preparing imidazopyridine derivatives LONZA LTD. (CH) 1996-03-12 US claimed
CN-1107848-A Preparation of imidazopyridir derivative LONZA AG (CH) 1995-09-06 CN claimed
EP-0656358-A1 Process for the preparation of imidazopyridinderivatives LONZA AG (CH) 1995-06-07 EP claimed
EP-0627433-A1 PROCESS FOR PRODUCING IMIDAZOPYRIDINE DERIVATIVE AND INTERMEDIATE Eisai Co., Ltd. (JP) 1994-12-07 EP claimed
EP-0201193-B1 CARBOXANILIDES AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-10-24 EP claimed
EP-0149537-B1 PROCESS FOR THE SYNTHESIS OF AMINONITROPYRIDINES ELI LILLY AND COMPANY (US) 1988-07-13 EP claimed
EP-0136730-B1 2-AMINONITROPYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1988-04-27 EP claimed
US-4552967-A Process for the synthesis of intermediates in the preparation of diaminopyridines ELI LILLY AND COMPANY (US) 1985-11-12 US claimed
EP-0149537-A2 Process for the synthesis of aminonitropyridines ELI LILLY AND COMPANY (US) 1985-07-24 EP claimed
US-3933498-A Fogged, direct positive silver halide emulsions containing a bleach inhibiting compound and a Dmin maintainer compound E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-20 US claimed