Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5787913 | 0.83 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL24335036 | 0.81 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL7247539 | 0.80 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL5785800 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5787610 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5788345 | 0.78 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL5315322 | 0.78 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL5787163 | 0.78 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL5789241 | 0.76 | MAPT (0.83) | PTGS2PTGS1 | |
| SCHEMBL5787875 | 0.75 | PTGS2 (0.78) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254119-B1 | PYRIMIDINE DERIVATIVES AS SELECTIVE INHIBITORS OF COX-2 | GLAXO GROUP LTD (GB) | 2006-04-12 | — | — | EP | disclosed |
| US-6780870-B2 | TREATMENT OF THE PAIN (BOTH CHRONIC AND ACUTE), FEVER AND INFLAMMATION OF A VARIETY OF CONDITIONS AND DISEASES MEDIATED BY COX-2 | SMITHKLINE BEECHAM CORPORATION | 2004-08-24 | — | — | US | disclosed |
| EP-1254119-A1 | PYRIMIDINE DERIVATIVES AS SELECTIVE INHIBITORS OF COX-2 | GLAXO GROUP LIMITED (GB) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001058881-A1 | PYRIMIDINE DERIVATIVES AS SELECTIVE INHIBITORS OF COX-2 | GLAXO GROUP LIMITED (GB) | 2001-08-16 | — | — | WO | disclosed |