Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528724 | 0.86 | GHSR (1.00) | GHSRCYP2D6KCNH2AVPR1BCASR | |
| SCHEMBL20528727 | 0.86 | GHSR (1.00) | GHSRCYP2D6KCNH2AVPR1BCASR | |
| SCHEMBL5823984 | 0.83 | CYP2D6 (0.76) | GHSRCYP2D6KCNH2AVPR1BHTR2C | |
| SCHEMBL5792841 | 0.82 | GHSR (0.65) | GHSRCYP2D6KCNH2AVPR1BCASR | |
| SCHEMBL5791040 | 0.80 | CYP2D6 (0.60) | GHSRCYP2D6KCNH2CASRHTR2C | |
| SCHEMBL5791022 | 0.78 | GHSR (0.85) | GHSRCYP2D6KCNH2AVPR1BCASR | |
| SCHEMBL20528715 | 0.77 | GHSR (0.83) | GHSRCYP2D6KCNH2AVPR1BHTR2C | |
| SCHEMBL20528716 | 0.77 | GHSR (0.83) | GHSRCYP2D6KCNH2AVPR1BHTR2C | |
| SCHEMBL20528775 | 0.77 | GHSR (0.82) | GHSRCYP2D6KCNH2AVPR1BHTR2C | |
| SCHEMBL20528830 | 0.77 | GHSR (0.83) | GHSRCYP2D6KCNH2AVPR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |