Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 3/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.71 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 2/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.51 |
| ▸ | STS | P08842 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25490795 | 1.00 | PTPN2 (0.71) | PTPN2PTPN1SERPINE1SCN1ASCN2A | |
| SCHEMBL27613024 | 0.89 | SERPINE1 (0.61) | PTPN2PTPN1SERPINE1SCN1ASCN2A | |
| SCHEMBL7407145 | 0.88 | PTPN2 (0.61) | PTPN2PTPN1SERPINE1SCN1ASCN2A | |
| SCHEMBL1839004 | 0.85 | SCN1A (0.75) | PTPN2PTPN1SCN1ASCN2ASCN3A | |
| SCHEMBL9421310 | 0.82 | SERPINE1 (0.58) | PTPN2PTPN1SERPINE1SCN1ASCN2A | |
| SCHEMBL30540804 | 0.82 | SERPINE1 (0.58) | PTPN2PTPN1SERPINE1SCN1ASCN2A | |
| SCHEMBL777809 | 0.82 | SERPINE1 (0.58) | PTPN2PTPN1SERPINE1SCN1ASCN2A | |
| SCHEMBL2589481 | 0.82 | SERPINE1 (0.53) | PTPN2PTPN1SERPINE1SCN1ASCN2A | |
| SCHEMBL31113478 | 0.81 | PTPN2 (0.57) | PTPN2PTPN1SCN1ASCN2ASCN3A | |
| SCHEMBL1976081 | 0.81 | STS (0.62) | PTPN2PTPN1SERPINE1SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745212-B | Spiro derivatives of substituted 4, 5-dihydropyrazolo [3,4-c ] pyridin-2-ones and uses thereof | 四川海思科制药有限公司 | 2017-09-12 | — | — | CN | disclosed |
| EP-1505966-A4 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2006-08-30 | — | — | EP | disclosed |
| EP-1505966-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003099276-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |