Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 13/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791597 | 0.82 | KDM1A (0.46) | TAAR1F2 | |
| SCHEMBL5794323 | 0.79 | XIAP (0.46) | TAAR1XIAP | |
| SCHEMBL5795407 | 0.79 | XIAP (0.46) | TAAR1XIAP | |
| SCHEMBL4836888 | 0.78 | PSEN1 (0.45) | F2 | |
| SCHEMBL4841221 | 0.78 | PSEN1 (0.45) | F2 | |
| SCHEMBL4845937 | 0.78 | PSEN1 (0.45) | F2 | |
| SCHEMBL4843024 | 0.78 | PSEN1 (0.45) | F2 | |
| SCHEMBL5794883 | 0.78 | XIAP (0.37) | TAAR1XIAP | |
| SCHEMBL5791328 | 0.78 | XIAP (0.37) | TAAR1XIAP | |
| SCHEMBL4841586 | 0.77 | PSEN1 (0.50) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | claimed |