Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791600 | 0.82 | TAAR1 (0.41) | F2TAAR1 | |
| SCHEMBL5794319 | 0.79 | KDM1A (0.45) | KDM1A | |
| SCHEMBL5795404 | 0.79 | KDM1A (0.45) | KDM1A | |
| SCHEMBL5791325 | 0.78 | KDM1A (0.49) | KDM1A | |
| SCHEMBL5794880 | 0.78 | KDM1A (0.49) | KDM1A | |
| SCHEMBL5791864 | 0.77 | KDM1A (0.42) | KDM1AF2TAAR1FAAHALDH1A1 | |
| SCHEMBL5790580 | 0.73 | KDM1A (0.43) | KDM1AF2FAAHALDH1A1CYP3A4 | |
| SCHEMBL5763037 | 0.72 | KDM1A (0.54) | KDM1AALDH1A1 | |
| SCHEMBL5762783 | 0.72 | KDM1A (0.54) | KDM1AALDH1A1 | |
| SCHEMBL5794093 | 0.72 | KDM1A (0.45) | KDM1AF2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | claimed |