Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776144 | 0.87 | HTR2C (0.57) | SIGMAR1TMEM97 | |
| SCHEMBL5788833 | 0.85 | SIGMAR1 (0.46) | SIGMAR1TMEM97 | |
| SCHEMBL5790811 | 0.85 | SIGMAR1 (0.61) | SIGMAR1TMEM97 | |
| SCHEMBL5792422 | 0.85 | SLC6A4 (0.47) | SIGMAR1TMEM97 | |
| SCHEMBL5792435 | 0.82 | SIGMAR1 (0.42) | SIGMAR1TMEM97 | |
| SCHEMBL3742011 | 0.81 | TMEM97 (0.42) | SIGMAR1TMEM97 | |
| SCHEMBL5789157 | 0.81 | TMEM97 (0.42) | SIGMAR1TMEM97 | |
| SCHEMBL28922110 | 0.75 | SIGMAR1 (0.46) | SIGMAR1TMEM97OPRK1 | |
| SCHEMBL29288546 | 0.75 | SIGMAR1 (0.60) | SIGMAR1TMEM97 | |
| SCHEMBL15805067 | 0.74 | TMEM97 (1.00) | SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016884-A9 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2006-03-16 | — | — | WO | disclosed |