Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 11/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792639 | 0.83 | KDM1A (0.56) | KDM1ABRD4SRD5A1HRH3 | |
| SCHEMBL5761078 | 0.78 | KDM1A (0.39) | XIAPKDM1ASMN1; SMN2NPSR1 | |
| SCHEMBL5763516 | 0.78 | KDM1A (0.39) | XIAPKDM1ASMN1; SMN2NPSR1 | |
| SCHEMBL5763400 | 0.78 | KDM1A (0.39) | XIAPKDM1ASMN1; SMN2NPSR1 | |
| SCHEMBL4840227 | 0.78 | PSEN1 (0.51) | KDM1A | |
| SCHEMBL4833092 | 0.78 | PSEN1 (0.51) | KDM1A | |
| SCHEMBL4842830 | 0.78 | PSEN1 (0.51) | KDM1A | |
| SCHEMBL4841145 | 0.78 | PSEN1 (0.51) | KDM1A | |
| SCHEMBL4837139 | 0.78 | PSEN1 (0.51) | KDM1A | |
| SCHEMBL4840677 | 0.78 | PSEN1 (0.51) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |