Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 6/20 | 0.36 |
| ▸ | FPR1 | P21462 | 5/20 | 0.36 |
| ▸ | XIAP | P98170 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761078 | 1.00 | KDM1A (0.39) | KDM1ASMN1; SMN2NPSR1NAAAFPR2 | |
| SCHEMBL5763400 | 1.00 | KDM1A (0.39) | KDM1ASMN1; SMN2NPSR1NAAAFPR2 | |
| SCHEMBL5763512 | 0.81 | KDM1A (0.56) | KDM1AF2RL1 | |
| SCHEMBL5763397 | 0.81 | KDM1A (0.56) | KDM1AF2RL1 | |
| SCHEMBL5761075 | 0.81 | KDM1A (0.56) | KDM1AF2RL1 | |
| SCHEMBL5762788 | 0.80 | ALDH1A1 (0.41) | KDM1AFPR2FPR1XIAP | |
| SCHEMBL5763042 | 0.80 | ALDH1A1 (0.41) | KDM1AFPR2FPR1XIAP | |
| SCHEMBL5763995 | 0.80 | NAAA (0.46) | NAAAXIAPCTSL | |
| SCHEMBL5764623 | 0.80 | NAAA (0.46) | NAAAXIAPCTSL | |
| SCHEMBL5792641 | 0.78 | XIAP (0.44) | KDM1ASMN1; SMN2NPSR1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | claimed |
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |