Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NMBR | P28336 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037597 | 0.83 | SIRT2 (0.45) | SIRT2CYP11B1CYP11B2NMBRENPP2 | |
| SCHEMBL4382643 | 0.82 | SIRT2 (0.54) | SIRT2CYP11B1CYP11B2ENPP2 | |
| SCHEMBL10815629 | 0.81 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2NMBRENPP2 | |
| Hydrochloric Acid SCHEMBL7987252 | 0.80 | SIRT2 (0.53) | SIRT2CYP11B1CYP11B2ENPP2 | |
| SCHEMBL2796109 | 0.79 | SIRT2 (0.52) | SIRT2CYP11B1CYP11B2FLT3TYRO3 | |
| SCHEMBL3821641 | 0.79 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2NMBRENPP2 | |
| SCHEMBL7269738 | 0.78 | SIRT2 (0.50) | SIRT2CYP11B1CYP11B2NMBRENPP2 | |
| SCHEMBL3976810 | 0.78 | SIRT2 (0.45) | SIRT2CYP11B1CYP11B2NMBRENPP2 | |
| SCHEMBL7977246 | 0.77 | SIRT2 (0.43) | SIRT2 | |
| SCHEMBL1039638 | 0.76 | SIRT2 (0.43) | SIRT2CYP11B1CYP11B2NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006005726-A2 | HETEROCYCLIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2006-01-19 | — | — | WO | disclosed |