Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | EPRS1 | P07814 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.60 |
| ▸ | PTGES | O14684 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788828 | 0.91 | DHODH (0.86) | DHODHALDH1A1GAAEPRS1MEN1 | |
| SCHEMBL26073753 | 0.90 | DHODH (0.89) | DHODHALDH1A1GAAEPRS1MEN1 | |
| SCHEMBL117430 | 0.88 | EPRS1 (0.79) | DHODHALDH1A1GAAEPRS1MEN1 | |
| SCHEMBL3232504 | 0.87 | DHODH (0.80) | DHODHALDH1A1GAAEPRS1MEN1 | |
| SCHEMBL1903454 | 0.87 | DHODH (0.94) | DHODHALDH1A1GAAMEN1KMT2A | |
| SCHEMBL26073763 | 0.86 | DHODH (0.78) | DHODHALDH1A1GAAEPRS1MEN1 | |
| SCHEMBL23590306 | 0.86 | DHODH (0.82) | DHODHALDH1A1GAAEPRS1MEN1 | |
| SCHEMBL31490621 | 0.86 | DHODH (0.73) | DHODHALDH1A1GAAEPRS1MEN1 | |
| SCHEMBL31490624 | 0.86 | DHODH (0.78) | DHODHALDH1A1GAAEPRS1MEN1 | |
| SCHEMBL6186359 | 0.86 | DHODH (0.85) | DHODHALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034512-A2 | PHENYL-SUBSTITUTED QUINOLINE AND QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006034512-A2 | PHENYL-SUBSTITUTED QUINOLINE AND QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006034491-A2 | PHENYL-SUBSTITUTED QUINOLINE AND QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |