Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FABP7 | O15540 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319074 | 1.00 | HTT (0.46) | HTTFABP7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5794818 | 0.92 | FABP7 (0.47) | HTTFABP7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL13666002 | 0.90 | FABP7 (0.40) | HTTFABP7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL13526597 | 0.90 | FABP7 (0.40) | HTTFABP7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL2051184 | 0.90 | ALDH1A1 (0.47) | HTTFABP7ALDH1A1KDM4EMEN1 | |
| SCHEMBL5541230 | 0.85 | FABP7 (0.42) | HTTFABP7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL15681894 | 0.82 | MAPT (0.47) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL11052486 | 0.82 | TLR4 (0.36) | HTTFABP7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL6752744 | 0.82 | TLR4 (0.36) | HTTFABP7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11052484 | 0.82 | TLR4 (0.36) | HTTFABP7L3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012277-A2 | BIOCATALYTIC PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED PRAMIPEXOLE | AMR TECHNOLOGY, INC. (US) | 2006-02-02 | — | — | WO | claimed |
| WO-2006012277-A2 | BIOCATALYTIC PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED PRAMIPEXOLE | AMR TECHNOLOGY, INC. (US) | 2006-02-02 | — | — | WO | disclosed |
| US-6261813-B1 | ACYLATING PACLITAXEL WITH BIFUNCTIONAL ACYL DONOR USING HYDROLASE TO FORM ACTIVATED ACYL ESTER OR CARBONATE, THEN ACYLATING NUCLEOPHILE WITH ACTIVATED ESTER OR CARBONATE IN PRESENCE OF HYDROLASE; IMPROVED WATER SOLUBILITY | ALBANY MOLECULAR RESEARCH, INC. | 2001-07-17 | — | — | US | disclosed |