Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793058 | 1.00 | SLC7A5 (0.57) | SLC7A5TAAR1HDAC8SLC6A2ESR1 | |
| SCHEMBL17229173 | 0.87 | SLC7A5 (0.41) | SLC7A5DPP4 | |
| SCHEMBL6521570 | 0.85 | SLC7A5 (0.59) | SLC7A5TAAR1HDAC8SLC6A2ESR1 | |
| SCHEMBL28148514 | 0.85 | SLC7A5 (0.59) | SLC7A5TAAR1HDAC8SLC6A2ESR1 | |
| SCHEMBL6586336 | 0.85 | ALPI (0.58) | SLC7A5HDAC8 | |
| SCHEMBL6593251 | 0.85 | ALPI (0.58) | SLC7A5HDAC8 | |
| SCHEMBL607242 | 0.83 | SLC7A5 (0.56) | SLC7A5TAAR1HDAC8SLC6A2ESR1 | |
| SCHEMBL598432 | 0.83 | SLC7A5 (0.56) | SLC7A5TAAR1HDAC8SLC6A2ESR1 | |
| SCHEMBL29159209 | 0.81 | SLC7A5 (0.54) | SLC7A5TAAR1HDAC8SLC6A2ESR1 | |
| SCHEMBL27680265 | 0.81 | SLC7A5 (0.67) | SLC7A5TAAR1HDAC8SLC6A2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012277-A2 | BIOCATALYTIC PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED PRAMIPEXOLE | AMR TECHNOLOGY, INC. (US) | 2006-02-02 | — | — | WO | disclosed |
| WO-2003057896-A1 | METHODS FOR PREPARING ANTHRACYCLINONE DERIVATIVES AND ANTHRACYCLINONE DERIVATIVES PER SE | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-07-17 | — | — | WO | disclosed |