Sugi Predict

Sugi Predict / Compounds / SCHEMBL607242

SCHEMBL607242

SCHEMBL607242

C=CCOC(=O)C(N)Cc1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 1/20 0.56
▸ KDM4E B2RXH2 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ HPGD P15428 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ HDAC8 Q9BY41 2/20 0.43
▸ TAAR1 Q96RJ0 3/20 0.43
▸ SLC6A2 P23975 1/20 0.43
▸ ESR1 P03372 2/20 0.42
▸ ESR2 Q92731 2/20 0.42
▸ CYP3A4 P08684 1/20 0.40
▸ DPP4 P27487 1/20 0.40
▸ MIF P14174 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598432 1.00 SLC7A5 (0.56) SLC7A5KDM4EALDH1A1TP53HPGD
Tyrosine SCHEMBL27709789 0.94 SLC7A5 (0.67) SLC7A5KDM4EALDH1A1HSD17B10CYP3A4
Tyrosine SCHEMBL28813646 0.91 SLC7A5 (0.61) SLC7A5KDM4EHSD17B10HDAC8
SCHEMBL4268012 0.88 ALDH1A1 (0.42) SLC7A5ALDH1A1HSD17B10CYP3A4DPP4
SCHEMBL10348263 0.86 SMN1; SMN2 (0.41) SLC7A5ALDH1A1HSD17B10CYP3A4DPP4
SCHEMBL1079463 0.86 ALPI (0.56) SLC7A5ALDH1A1HSD17B10HDAC8CYP3A4
SCHEMBL2515423 0.86 ALPI (0.56) SLC7A5ALDH1A1HSD17B10HDAC8CYP3A4
SCHEMBL1692431 0.86 ALPI (0.56) SLC7A5ALDH1A1HSD17B10HDAC8CYP3A4
Hydrochloric Acid SCHEMBL26128753 0.85 TPH1 (0.41) SLC7A5ALDH1A1HSD17B10CYP3A4DPP4
Hydrochloric Acid SCHEMBL26128751 0.85 TPH1 (0.41) SLC7A5ALDH1A1HSD17B10CYP3A4DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3634944-A1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS Medtronic, Inc. (US) 2020-04-15 — — EP claimed
CN-110637007-A Synthesis of tyrosine-derived diphenol monomers 美敦力公司 2019-12-31 — — CN claimed
US-10442757-B2 Synthesis of tyrosine derived diphenol monomers MEDTRONIC, INC. (US) 2019-10-15 — — US claimed
US-20180354892-A1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS TYRX, INC. (US) 2018-12-13 — — US claimed
WO-2018226340-A1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS TYRX, INC. (US) 2018-12-13 — — WO claimed
JP-6321916-A — — None — — JP disclosed
EP-4387673-A1 PROCESS FOR THE PREPARATION OF PEGYLATED ADRENOMEDULLIN, ITS INTERMEDIATES AND USE THEREOF Bayer Aktiengesellschaft (DE) 2024-06-26 — — EP disclosed
WO-2023217590-A1 POLYAMIDE MICROCAPSULES FIRMENICH SA (CH) 2023-11-16 — — WO disclosed
WO-2023021173-A1 PROCESS FOR THE PREPARATION OF PEGYLATED ADRENOMEDULLIN, ITS INTERMEDIATES AND USE THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2023-02-23 — — WO disclosed
CN-110330600-B Low-sensitivity wet-mixed mortar plasticizer and preparation method thereof 科之杰新材料集团有限公司 2022-04-22 — — CN disclosed
CN-110358021-B Cross-linking type wet-mixed mortar plasticity-maintaining agent and preparation method thereof 科之杰新材料集团有限公司 2022-04-22 — — CN disclosed
US-20210115087-A1 CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS UNIV ROCHESTER (US) 2021-04-22 — — US disclosed
WO-1999052962-A1 THE CONSTRUCTION OF COPOLYMER LIBRARIES RUTGERS, THE STATE UNIVERSITY (US) 1999-10-21 — — WO disclosed
WO-1999024391-A1 RADIO-OPAQUE POLYMER BIOMATERIALS RUTGERS, THE STATE UNIVERSITY (US) 1999-05-20 — — WO disclosed
WO-1999024490-A1 STRICTLY ALTERNATING POLY(ALKYLENE OXIDE ETHER) COPOLYMERS RUTGERS, THE STATE UNIVERSITY (US) 1999-05-20 — — WO disclosed
WO-1998011923-A1 IDENTIFICATION OF AGENTS THAT PROTECT AGAINST INFLAMMATORY INJURY TO NEURONS BAYLOR COLLEGE OF MEDICINE (US) 1998-03-26 — — WO disclosed
JP-H06321916-A PRODUCTION OF 3,6-BIS((4-HYDROXYPHENYL)METHYL)-2,5-DIKETOPIPERAZINE MITSUI TOATSU CHEM INC 1994-11-22 — — JP disclosed
US-5219986-A Polyanhydroaspartic acid and method of dry manufacture of polymers CYGNUS CORPORATION (US) 1993-06-15 — — US disclosed
US-4638045-A CONTROLLED RELEASE OF PHARMACOLOGICALLY ACTIVE LIGANDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1987-01-20 — — US disclosed
US-3963691-A POLYPEPTIDES, PEPTIZATION MERCK & CO., INC. (US) 1976-06-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210115087-A1 CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS SHH, SMO, DACH1 SLC7A5 3485/4885KDM4E 3988/4885ALDH1A1 4638/4885
US-10442757-B2 Synthesis of tyrosine derived diphenol monomers TYR, TH, TYRO3 SLC7A5 1220/4885KDM4E 372/4885ALDH1A1 1997/4885
US-20180354892-A1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS TYR, TH, DDT SLC7A5 1198/4885KDM4E 331/4885ALDH1A1 2169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.