Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793590 | 1.00 | HRH3 (0.51) | HRH3ACHERAD52SLC6A2HRH1 | |
| SCHEMBL5793595 | 1.00 | HRH3 (0.51) | HRH3ACHERAD52SLC6A2HRH1 | |
| SCHEMBL5796399 | 0.89 | HRH3 (0.61) | HRH3ACHERAD52SLC6A2HRH1 | |
| SCHEMBL5796833 | 0.89 | HRH3 (0.61) | HRH3ACHERAD52SLC6A2HRH1 | |
| SCHEMBL5796832 | 0.89 | HRH3 (0.61) | HRH3ACHERAD52SLC6A2HRH1 | |
| SCHEMBL5908092 | 0.89 | HRH3 (0.61) | HRH3ACHERAD52SLC6A2HRH1 | |
| SCHEMBL5820304 | 0.88 | HRH3 (0.51) | HRH3ACHERAD52SLC6A2HRH1 | |
| SCHEMBL5908085 | 0.88 | HRH3 (0.51) | HRH3ACHERAD52SLC6A2HRH1 | |
| SCHEMBL5820307 | 0.88 | HRH3 (0.51) | HRH3ACHERAD52SLC6A2HRH1 | |
| SCHEMBL5796240 | 0.88 | ALDH1A1 (0.56) | HRH3ACHERAD52SLC6A2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006024955-A1 | AZABICYCLIC AMINE HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-03-09 | — | — | WO | claimed |
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | PFIZER INC | 2006-03-02 | — | — | US | claimed |
| WO-2006024955-A1 | AZABICYCLIC AMINE HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-03-09 | — | — | WO | disclosed |
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | PFIZER INC | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | HRH3, HRH4, HRH2 | HRH3 1/4885ACHE 227/4885RAD52 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.