⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226035 | 0.75 | GAA (0.41) | — | |
| Hydrochloric Acid SCHEMBL10718549 | 0.73 | MEN1 (0.39) | — | |
| SCHEMBL2704673 | 0.65 | GAA (0.41) | — | |
| SCHEMBL22033216 | 0.64 | GAA (0.45) | — | |
| SCHEMBL205451 | 0.64 | GAA (0.39) | — | |
| SCHEMBL6917932 | 0.64 | GAA (0.39) | — | |
| SCHEMBL331758 | 0.64 | GAA (0.39) | — | |
| SCHEMBL155143 | 0.64 | ALDH1A1 (0.45) | — | |
| SCHEMBL8091899 | 0.62 | NOX1 (0.48) | — | |
| SCHEMBL56711 | 0.62 | GAA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2616 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| US-11744824-B2 | 2-amino-3-carbonyl imidazopyridine and pyrazolopyridine compounds | 1ST Biotherapeutics, Inc. (KR) | 2023-09-05 | — | — | US | claimed |
| EP-4214207-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1st Biotherapeutics, Inc. (KR) | 2023-07-26 | — | — | EP | claimed |
| CN-116457355-A | 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds | 第一生物治疗股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| EP-3720858-B1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2023-06-07 | — | — | EP | claimed |
| CN-116102584-A | 3, 3-gem difluoro allyl compound, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2023-05-12 | — | — | CN | claimed |
| US-20220396579-A1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2022-12-15 | — | — | US | claimed |
| US-11302874-B2 | Organic electroluminescent compound and organic electroluminescent device comprising the same | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. | 2022-04-12 | — | — | US | claimed |
| US-20220087985-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1ST Biotherapeutics, Inc. (KR) | 2022-03-24 | — | — | US | claimed |
| CN-113950475-A | Organic electroluminescent compounds and organic electroluminescent device comprising the same | 罗门哈斯电子材料韩国有限公司 | 2022-01-18 | — | — | CN | claimed |
| EP-0178035-B1 | ANTI-INFLAMMATORY 1,N-DIARYLPYRAZOL-3-AMINES, COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | FISONS plc (GB) | 1990-01-03 | — | — | EP | claimed |
| EP-0233140-B1 | LUBRICANT ADDITIVES CONTAINING SULPHUR AND NITROGEN | CIBA-GEIGY AG (CH) | 1989-11-08 | — | — | EP | claimed |
| EP-0166696-B1 | LUBRICANT ADDITIVES | CIBA-GEIGY AG (CH) | 1989-07-19 | — | — | EP | claimed |
| US-4784929-A | LATENT IMAGES | MINOLTA CAMERA KABUSHIKI KAISHA (JP) | 1988-11-15 | — | — | US | claimed |
| EP-0120589-B1 | IMIDAZO-HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-08 | — | — | EP | claimed |
| EP-0233140-A1 | Lubricant additives containing sulphur and nitrogen | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | claimed |
| US-4621084-A | CARDIOTONIC, ANTIULCER | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-04 | — | — | US | claimed |
| EP-0166696-A2 | Lubricant additives | CIBA-GEIGY AG (CH) | 1986-01-02 | — | — | EP | claimed |
| EP-0120589-A1 | Imidazo-heterocyclic compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-03 | — | — | EP | claimed |
| US-4113867-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-12 | — | — | US | claimed |