Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 6/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | PDE6D | O43924 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807103 | 0.90 | GHSR (0.73) | GHSRCYP2D6KCNH2BRD4ABCC1 | |
| SCHEMBL20528727 | 0.84 | GHSR (1.00) | GHSRCYP2D6KCNH2BRD4AVPR1B | |
| SCHEMBL20528724 | 0.84 | GHSR (1.00) | GHSRCYP2D6KCNH2BRD4AVPR1B | |
| SCHEMBL5791022 | 0.83 | GHSR (0.85) | GHSRCYP2D6KCNH2BRD4AVPR1B | |
| SCHEMBL20528718 | 0.82 | GHSR (0.71) | GHSRCYP2D6KCNH2BRD4AVPR1B | |
| SCHEMBL5791482 | 0.82 | GHSR (0.71) | GHSRCYP2D6KCNH2BRD4AVPR1B | |
| SCHEMBL5791450 | 0.81 | GHSR (0.73) | GHSRCYP2D6KCNH2BRD4 | |
| SCHEMBL20528765 | 0.79 | GHSR (0.72) | GHSRCYP2D6KCNH2BRD4 | |
| SCHEMBL20528767 | 0.79 | GHSR (0.72) | GHSRCYP2D6KCNH2BRD4 | |
| SCHEMBL20528751 | 0.79 | GHSR (0.68) | GHSRCYP2D6KCNH2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |