Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036318 | 0.72 | ANPEP (0.50) | ANPEPHDAC4HDAC7HDAC5KMT2A | |
| SCHEMBL15722171 | 0.72 | HRH3 (0.41) | ANPEPHDAC4HDAC7HDAC5ALDH1A1 | |
| SCHEMBL144326 | 0.71 | KMT2A (0.65) | MEN1KMT2ANPSR1 | |
| SCHEMBL6307418 | 0.70 | XIAP (0.54) | ANPEPMEN1KMT2AXIAP | |
| SCHEMBL1207850 | 0.70 | HDAC4 (0.51) | ANPEPMTNR1AMTNR1BHDAC4HDAC7 | |
| SCHEMBL13137661 | 0.70 | ANPEP (0.47) | ANPEPMTNR1AMTNR1BHDAC4HDAC7 | |
| SCHEMBL6634791 | 0.69 | MTNR1A (0.46) | MTNR1AMTNR1BHDAC4HDAC7HDAC5 | |
| SCHEMBL11305981 | 0.69 | XIAP (0.44) | ANPEPALDH1A1MEN1KMT2AXIAP | |
| SCHEMBL2187484 | 0.69 | ANPEP (0.59) | ANPEPHDAC4HDAC7HDAC5SMN1; SMN2 | |
| SCHEMBL30633009 | 0.69 | ANPEP (0.59) | ANPEPHDAC4HDAC7HDAC5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006020070-A2 | INDANYLAMINO URACILS AND THEIR USE AS ANTIOXIDANTS AND NEUROPROTECTANTS | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2006-02-23 | — | — | WO | disclosed |