Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21183309 | 0.83 | APP (0.38) | APPALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL19996093 | 0.82 | ALDH1A1 (0.50) | APPALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL20014274 | 0.82 | ALDH1A1 (0.50) | APPALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL19038363 | 0.79 | APP (0.37) | APPALDH1A1TSHRACACBTRPA1 | |
| SCHEMBL8720901 | 0.76 | KMT2A (0.47) | APPALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL17736164 | 0.76 | IDO1 (0.42) | TDP1ACACBTRPA1 | |
| SCHEMBL8244501 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL10632743 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL165131 | 0.75 | ALDH1A1 (0.64) | APPALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL19003674 | 0.75 | ALDH1A1 (0.49) | APPALDH1A1TSHRCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006007209-A2 | PRESSURE AND TEMPERATURE SENSITIVE MATERIAL | LEATECH, LLC (US) | 2006-01-19 | — | — | WO | disclosed |
| US-20050288475-A1 | Pressure and temperature sensitive material | LEATECH LLC | 2005-12-29 | — | — | US | disclosed |