Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.57 |
| ▸ | ACACB | O00763 | 1/20 | 0.55 |
| ▸ | ACACA | Q13085 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 8/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035472 | 0.98 | ACLY (0.61) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL27754242 | 0.98 | ACLY (0.61) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL7161723 | 0.98 | ACLY (0.61) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL3958577 | 0.93 | ACLY (0.54) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL2977206 | 0.88 | ACLY (0.47) | ACLYACACBACACAPPARATDP1 | |
| SCHEMBL7222208 | 0.87 | ACLY (0.70) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL4190226 | 0.85 | ACLY (0.74) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL1832600 | 0.85 | ACLY (0.74) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL20474799 | 0.85 | ACLY (0.74) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL1836313 | 0.85 | ACLY (0.74) | ACLYACACBACACATBXAS1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522192-A | Substituted imidazolone derivatives, preparation and uses | GENFIT (FR) | 2009-09-02 | — | — | CN | disclosed |
| WO-2006035157-A2 | SUBSTITUTED N-(BENZYL)PHENYLACETAMIDE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME AS PPAR LIGANDS IN THE TREATMENT OF LIPID AND/OR GLUCIDIC DISORDERS | GENFIT (FR) | 2006-04-06 | — | — | WO | disclosed |