Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.77 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.57 |
| ▸ | ACP1 | P24666 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796409 | 0.86 | PDE10A (0.64) | PDE10ASLC2A1ACP1 | |
| SCHEMBL8269590 | 0.83 | PDE10A (1.00) | PDE10ASLC2A1ACP1 | |
| SCHEMBL8270983 | 0.83 | PDE10A (0.83) | PDE10ASLC2A1ACP1 | |
| SCHEMBL8268397 | 0.82 | PDE10A (0.72) | PDE10ASLC2A1ACP1 | |
| SCHEMBL8270941 | 0.82 | TOP2A (0.60) | PDE10ASLC2A1ACP1 | |
| SCHEMBL8269889 | 0.79 | PDE10A (0.69) | PDE10ASLC2A1ACP1 | |
| SCHEMBL15919345 | 0.78 | ACP1 (0.51) | PDE10AACP1RXFP1 | |
| SCHEMBL8270988 | 0.77 | PDE10A (0.73) | PDE10ASLC2A1ACP1 | |
| SCHEMBL8270997 | 0.77 | PDE10A (0.64) | PDE10ASLC2A1ACP1 | |
| SCHEMBL8269556 | 0.75 | PDE10A (0.78) | PDE10ASLC2A1ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034512-A2 | PHENYL-SUBSTITUTED QUINOLINE AND QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006034491-A2 | PHENYL-SUBSTITUTED QUINOLINE AND QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006034512-A2 | PHENYL-SUBSTITUTED QUINOLINE AND QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |