Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.59 |
| ▸ | PDE5A | O76074 | 1/20 | 0.57 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | ACP1 | P24666 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796409 | 0.94 | PDE10A (0.64) | TOP2APDE10ASLC2A1ACP1 | |
| SCHEMBL8270104 | 0.87 | PDE10A (0.61) | TOP2APDE10APDE5AELANESLC2A1 | |
| SCHEMBL8271027 | 0.87 | ACP1 (0.49) | TOP2APDE10APDE5AELANEACP1 | |
| SCHEMBL8270103 | 0.86 | PDE10A (0.56) | TOP2APDE10APDE5AELANESLC2A1 | |
| SCHEMBL8270101 | 0.86 | PDE10A (0.78) | TOP2APDE10APDE5AELANESLC2A1 | |
| SCHEMBL8269556 | 0.85 | PDE10A (0.78) | TOP2APDE10ASLC2A1ACP1 | |
| SCHEMBL8270100 | 0.84 | ACP1 (0.55) | TOP2APDE10APDE5AELANESLC2A1 | |
| SCHEMBL5795056 | 0.82 | PDE10A (0.77) | PDE10ASLC2A1ACP1 | |
| SCHEMBL8269553 | 0.81 | PDE10A (0.66) | TOP2APDE10APDE5ASLC2A1ACP1 | |
| SCHEMBL8268944 | 0.81 | PDE10A (0.48) | TOP2APDE10AACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034512-A2 | PHENYL-SUBSTITUTED QUINOLINE AND QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |