Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.58 |
| ▸ | GHSR | Q92847 | 14/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791737 | 1.00 | CYP2D6 (0.58) | CYP2D6GHSRKCNH2CYP3A4 | |
| SCHEMBL5791006 | 0.87 | CYP2D6 (0.67) | CYP2D6GHSRKCNH2CYP3A4 | |
| SCHEMBL5791730 | 0.87 | GHSR (0.73) | CYP2D6GHSRKCNH2CYP3A4 | |
| SCHEMBL5791009 | 0.86 | CYP2D6 (0.74) | CYP2D6GHSRKCNH2CYP3A4 | |
| SCHEMBL5791115 | 0.85 | GHSR (0.58) | CYP2D6GHSRKCNH2CYP3A4 | |
| SCHEMBL5790809 | 0.85 | GHSR (0.58) | CYP2D6GHSRKCNH2CYP3A4 | |
| SCHEMBL5791441 | 0.81 | GHSR (0.76) | CYP2D6GHSRKCNH2CYP3A4 | |
| SCHEMBL5820677 | 0.80 | GHSR (0.59) | CYP2D6GHSRKCNH2CYP3A4 | |
| SCHEMBL5793993 | 0.78 | CYP2D6 (0.73) | CYP2D6GHSRKCNH2CYP3A4 | |
| SCHEMBL16302710 | 0.74 | GHSR (0.86) | CYP2D6GHSRKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |