Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796468 | 0.81 | MAPK11 (0.52) | MAPK14MAPK13MAPK12MAPK11HRH4 | |
| SCHEMBL5798471 | 0.74 | MAPK11 (0.52) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5796486 | 0.73 | MAPK11 (0.51) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5795927 | 0.72 | MAPK11 (0.53) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5795836 | 0.72 | MAPK13 (0.48) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5795644 | 0.71 | MAPK11 (0.52) | MAPK14MAPK13MAPK12MAPK11ALOX5AP | |
| SCHEMBL5795840 | 0.71 | MAPK11 (0.48) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5795633 | 0.69 | MAPK11 (0.49) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5813843 | 0.67 | SCN9A (0.44) | HRH4 | |
| SCHEMBL5797338 | 0.65 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038734-A1 | PYRIDAZINONE DERIVATIVES CYTOKINES INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2006-04-13 | — | — | WO | disclosed |