Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.36 |
| ▸ | LGMN | Q99538 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5106374 | 0.92 | IKBKB (0.44) | IKBKBCHUKEPHA3CDK8 | |
| SCHEMBL14277278 | 0.91 | IKBKB (0.38) | IKBKBCHUKEPHA3LGMNCDK8 | |
| SCHEMBL5116053 | 0.81 | IKBKB (0.44) | IKBKBCHUKEPHA3CDK8 | |
| SCHEMBL14277270 | 0.81 | IKBKB (0.36) | IKBKBCHUKEPHA3LGMNCDK8 | |
| SCHEMBL5114616 | 0.80 | IKBKB (0.49) | IKBKBCHUKEPHA3CDK8 | |
| SCHEMBL14277280 | 0.80 | IKBKB (0.35) | IKBKBCHUKEPHA3LGMN | |
| SCHEMBL5114160 | 0.79 | CASP7 (0.42) | IKBKBCHUKEPHA3 | |
| SCHEMBL5106407 | 0.79 | IKBKB (0.42) | IKBKBCHUKEPHA3CDK8 | |
| SCHEMBL5117786 | 0.79 | CDK8 (0.42) | IKBKBCHUKEPHA3CDK8 | |
| SCHEMBL14277275 | 0.79 | LRRK2 (0.38) | IKBKBCHUKEPHA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651629-A1 | SUBSTITUTED BENZOTHIOPHENE COMPOUNDS AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2006-05-03 | — | — | EP | claimed |
| WO-2005012283-A1 | SUBSTITUTED BENZOTHIOPHENE COMPOUNDS AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-02-10 | — | — | WO | claimed |