Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CFD | P00746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16396429 | 0.85 | P2RX7 (0.55) | P2RX7NPC1RAB9ACFDALDH1A1 | |
| SCHEMBL23368468 | 0.83 | P2RX7 (0.54) | P2RX7NPC1RAB9ACFDALDH1A1 | |
| SCHEMBL28803282 | 0.83 | P2RX7 (0.51) | P2RX7NPC1RAB9ACFDALDH1A1 | |
| SCHEMBL5798126 | 0.83 | NPC1 (0.53) | P2RX7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11589808 | 0.82 | NPC1 (0.72) | NPC1RAB9AALDH1A1CASRMEN1 | |
| SCHEMBL19208424 | 0.82 | P2RX7 (0.56) | P2RX7NPC1RAB9ACFDALDH1A1 | |
| SCHEMBL19208309 | 0.81 | P2RX7 (0.55) | P2RX7NPC1RAB9ACFDTP53 | |
| SCHEMBL18967804 | 0.81 | P2RX7 (0.58) | P2RX7NPC1RAB9ACFDALDH1A1 | |
| SCHEMBL19208558 | 0.81 | P2RX7 (0.55) | P2RX7NPC1RAB9ACFDMEN1 | |
| SCHEMBL5797618 | 0.80 | P2RX7 (0.53) | P2RX7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006037468-A1 | HIV REVERSE TRANSCRIPTASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-04-13 | — | — | WO | claimed |